Women are widely assumed to be more talkative than men. Disconfirming this assumption, Mehl et al. (2007) provided the first empirical evidence that men and women do not differ significantly in daily word use, speaking about 16,000 words per day each. However, concerns were raised that their sample was too small to yield precise and generalizable estimates, and too age- and context-homogeneous to permit inferences beyond college students. This project replicates and extends the previous study of binary gender differences in daily word use to address these concerns. Pooling data for 2,197 participants (>5-fold the original sample size) from 22 samples (631,030 ambient audio recordings), it updates the estimates of women and men’s daily word use and evaluates the magnitude of their difference. It further explores the extent to which age (as a marker of developmental processes) and experienced stress (as a marker of biobehavioral coping processes) moderate this difference. Finally, it compares the general, age-, and stress-related gender-difference estimates for objectively-observed talkativeness (i.e., EAR-sampled daily word use) to the gender-difference estimates that emerge when looking at subjectively-rated talkativeness (i.e., self-reports of the respective Big Five Inventory item).