In this registered report ( N = 423), we investigated in a competitive intergroup context to what extent the perception of targets scoring high in grandiose narcissism varies depending on whether they belong to one’s own group or to an opposing outgroup. In a laboratory study, members of newly formed groups had direct contact with another group and competed for scarce resources. Contrary to our hypothesis, perceivers did not ascribe targets scoring high in narcissistic admiration higher status when they belonged to their ingroup versus the outgroup. Also unexpectedly, they did not like targets scoring high in narcissistic rivalry better when they belonged to their ingroup. Instead, our findings indicate that narcissistic admiration was generally linked to more dominant-expressive behavior and that participants had a stronger inclination to interpret a specific behavior as aggressive when it was shown by a member of the outgroup, rather than a member of the ingroup.

Abstract Objectives We aimed to investigate the effects of directly manipulating response style to simulated voice hearing on emotional and cognitive outcomes in a non‐clinical population. Design A between‐subjects design with one independent variable, response style (with two levels: mindful acceptance vs attentional avoidance). The dependent variables were subjective distress and anxiety (primary outcomes) and performance on a sustained attention task (secondary outcomes). Methods Participants were randomly assigned to one of two response styles (mindful acceptance vs. attentional avoidance). They completed a computerised attention task (continuous performance task) whilst listening to a simulation of voice hearing. Participants rated their experience of anxiety and distress before and after completing the sustained attention task which was used to measure their accuracy and response times. Results One hundred and one participants took part (mindful acceptance ( n  = 54); attentional avoidance ( n  = 47)). There were no statistically significant group differences on post‐test distress and anxiety scores, correct response rate or response times on the computerised attention task. Participants reported a range of different response styles along the spectrum of avoidance to acceptance, but this had no association with their assigned experimental condition. Adherence to task instructions was therefore low. Conclusions We are unable to conclude from this study whether experimentally inducing people to respond to voices under cognitively demanding conditions in an avoidant or accepting way has an impact on their emotional or cognitive outcomes. Further research should focus on the development of more robust and reliable procedures for inducing differences in response style under experimental conditions.

Working together (vs. individually) improves the performance of people from working-class contexts. Consequently, teams with a higher (vs. lower) percentage of individuals from working-class contexts perform better. However, previous research offers two competing mechanisms for this effect. On the one hand, research has provided evidence for a pathway through skills: people from working-class contexts more frequently engage in effective group processes when working together. On the other hand, there is evidence for a pathway through sense of fit: individuals from working-class contexts feel a greater sense of belonging in interdependent settings. In this registered report, we will provide the first simultaneous test of these two proposed mechanisms as the route to successful performance for working-class individuals in teams. Moreover, we will examine if meeting mode—i.e., the extent to which teams work together synchronously (vs. asynchronously)—serves as an important boundary condition for the performance of people from working-class contexts in teams. We hypothesize that the beneficial effects of working together for students from working-class contexts will be diminished when teams work together primarily asynchronously. Lastly, we will provide the first confirmatory test and extension in a real-world collegiate setting where students from working-class contexts are in the majority (in contrast to prior work where they were in the numerical minority). Taken together, this registered report will replicate and extend past research on contextual routes to reduce social class inequalities, and shed light on the mechanisms through which these routes operate.

Intact cognitive control is critical for goal-directed behavior and is widely studied in healthy and clinical populations using the error-related negativity (ERN). A common assumption in such studies is that ERNs recorded during different experimental paradigms reflect the same construct or functionally equivalent processes and that ERN is functionally distinct from other error-monitoring event-related potentials (ERPs; error positivity [Pe]), other neurophysiological indices of cognitive control (N2), and even other indices unrelated to cognitive control (visual N1). The present registered report represents a replication-plus-extension study of the psychometric validity of cognitive control ERPs (Riesel et al., 2013, Biological Psychology) and evaluated the convergent and divergent validity of ERN, Pe, N2, and visual N1 recorded during three paradigms (flanker, Stroop, Go/no-go). Data from 182 participants were collected from two study sites, and ERP psychometric reliability and validity were evaluated in comparison to ERPs and internalizing and externalizing symptoms. Findings supported replication of convergent and divergent validity of ERN, Pe, and Pe (error minus correct)—these ERPs correlated more with themselves across tasks than with other ERPs measured during the same task. Convergent validity of ERN across tasks was not replicated, despite high internal consistency. ERN was strongly correlated with N2 at levels similar or higher than those in support of convergent validity for other ERPs, although the present study failed to provide evidence of divergent validity for ERN and Pe from N2 or the theoretically-unrelated N1. ERN and ERN were unrelated to internalizing or externalizing symptoms. Present findings underscore the importance of considering the psychometric validity of ERPs as it provides a foundation for interpreting and comparing ERPs across different tasks and studies.

Registered Reports were introduced a decade ago to reduce data dredging and the selective reporting of “statistically significant” results in journal articles. Previous studies have examined the extent to which journals have adopted the procedure and the number of such articles published in these journals. This bibliometric study focuses on the subdiscipline that has most thoroughly adopted the procedure, experimental psychology, and compiles a more complete list of published Registered Reports than used in previous studies and estimates their prevalence in the experimental psychology literature using Web of Science for total article counts. Thirty-six experimental psychology journals were found to have adopted the procedure, but 11 had not published any Registered Reports by the end of 2023. One journal accounted for almost 30% of the 227 Registered Reports, and eight others for a further 50%. Registered Reports represented a small percentage of the total experimental psychology articles published over the period 2013–2023 at 1.2%. Lack of diffusion of Registered Reports through the subdiscipline that has most fully embraced it is likely due to it having little value within the academic incentive system. Future studies would benefit from journals more accurately identifying Registered Reports and the creation of a central registry.

Fear is a universal experience and fuels our response to cope with threat. Persistent fear, after the threat is no longer present, is a central symptom seen in a number of clinical conditions. Exposure therapy, the most common treatment to target fear, aims to reduce fear responses through repeated, controlled exposures to feared situations in the absence of the negative consequence, thus promoting extinction. However, this treatment is by no means effective for all people. This may be due to impaired extinction and the underlying mechanism of inhibitory retrieval. Intentional memory suppression has been shown to be a promising strategy to enhance this underlying inhibitory mechanism. We employed a newly developed paradigm combining aspects of the Think/No-Think procedure with fear extinction. Sixty-eight healthy participants learned 36 strong naturalistic reminder objects for aversive scenes. After learning, half of the objects were paired with an aversive scream (unconditioned stimulus/US). During the extinction phase, while viewing the objects, participants were instructed to repeatedly retrieve (Think instruction) or suppress (No-Think instruction) the corresponding scenes, or passively view the objects (View instruction). We hypothesised that intentional suppression would boost fear extinction, as shown by a reduced US expectancy to threat-conditioned objects that had been subject to memory suppression during extinction training compared to threat-conditioned objects that were passively viewed. Both intentional memory suppression and passive viewing reduced negative valence for upsetting scenes over time. Contrary to our hypothesis, the results indicated that intentional suppression (No-Think instruction) was not more effective in reducing US expectancy and fear than standard extinction (View instruction). Future research should address the limitation of self-reports by using physiological measures and examine whether intentional suppression may impact fear recovery and generalization following a longer extinction delay. The current findings show that, although intentional suppression can support inhibition of memories and reduce their valence, it may not be as effective as standard extinction methods in diminishing fear responses.

The development of the minimal self - distinguished in the facets sense of agency, body ownership, and interoception – has recently gained attention in developmental science. While research proposes the presence of minimal self facets in young children, interrelations among the three facets and cognitive mechanisms driving their development remain debated. Current theories suggest that minimal self facets are dynamic and plastic, affected by top-down processes and cognitive representations. To advance developmental theorizing, the present registered report had four aims. It a) examined how strongly the three minimal self facets are related, and b) investigated the impact of one central cognitive process – the internal working model (IWM) of attachment – on young children’s explicit self, and c), their minimal self. Furthermore, it d) explored whether the impact of the IWM is particularly strong in emotional contexts. A total of 120 fiveyear-old children from an urban German area participated. Established measures were used to assess all three minimal self facets, explicit selfconcept, and dimensional security of attachment IWM. We found no significant relations between the three minimal self facets and no prediction of minimal self facets by attachment security. Thus, the study provides no evidence for an influence of attachment IWM on minimal self facets in childhood. Exploratory analyses showed a relation between attachment categories and the malleability of sense of body ownership suggesting that a categorical approach to attachment is relevant for considerations of minimal self facets. We suggest that future research should integrate the sensorimotor grounding of attachment.

Abstract Single-cell multimodal omics technologies have empowered the profiling of complex biological systems at a resolution and scale that were previously unattainable. These biotechnologies have propelled the fast-paced innovation and development of data integration methods, leading to a critical need for their systematic categorisation, evaluation, and benchmark. Navigating and selecting the most pertinent integration approach poses a significant challenge, contingent upon the tasks relevant to the study goals and the combination of modalities and batches present in the data at hand. Understanding how well each method performs multiple tasks, including dimension reduction, batch correction, cell type classification and clustering, imputation, feature selection, and spatial registration, and at which combinations will help guide this decision. This study develops a much-needed guideline on choosing the most appropriate method for single-cell multimodal omics data analysis through a systematic categorisation and comprehensive benchmarking of current methods. The Stage 1 protocol for this Registered Report was accepted in principle on 30th July 2024. The protocol, as accepted by the journal, can be found at https://springernature.figshare.com/articles/journal_contribution/Multi-task_benchmarking_of_single-cell_multimodal_omics_integration_methods/26789902 .

Aim Resilience is the ability to adapt well to adversity, trauma, tragedy, threats, or significant sources of stress, and it can be learned and developed in anyone. The psychological, social, and mental health of Hong Kong youths has been substantially adversely affected by protests that arose in 2019–2020 and the social and economic impacts of the COVID-19 pandemic in 2020–2022. Nursing students must cope with academic stress and must often overcome unexpected adversity during clinical placements and in transitioning from a student to a registered nurse in their final year of study. Therefore, this study aims to introduce a nurse-led stress management and resilience training (SMART) programme for final-year nursing undergraduates and examine the effectiveness of the programme in improving the students’ resilience and mental health outcomes. Methods The proposed project will involve a randomised wait-list-controlled trial. Four hundred final-year nursing undergraduates will be randomly assigned to a wait-list control or intervention group. They will be required to attend three 2.5-hour face-to-face training sessions delivered biweekly. The SMART programme will be delivered by an experienced team, comprising an experienced nurse educator and a certified counsellor. The levels of resilience, stress, anxiety, and depressive symptoms of both groups will be measured using the Connor–Davidson Resilience Scale 10 and the Depression Anxiety and Stress Scale 21 at four time points. Results The results of the proposed project will be shared after the completion of the study. Conclusion This study will evaluate the effectiveness of the SMART programme among nursing undergraduates.

We evaluate the ability of the asset pricing models of Liu, Stambaugh and Yuan (2019), hereafter LSY, and Fama and French (2018) to price Chinese stocks. Following the methodology specified in the pre-registered report (Gharghori and Nguyen, 2025), we employ spanning regressions and maximum Sharpe ratios to compare models. Our results show that the LSY models exhibit higher Sharpe ratios and outperform both conventional and modified Fama-French models in spanning regressions. In contrast to developed markets, the investment factor carries a negative premium in China. Additionally, the LSY models do not span this factor. Consequently, the model that delivers the highest Sharpe ratio is the one that augments the LSY four-factor model with the investment factor of Fama-French.

The cognitive mechanisms and benefits of active learning in early child development are poorly understood. The current study investigated 20–23‐month‐old infants’ curiosity‐driven information selection in a novel word learning task, designed to identify any potential advantage for active learning over passive learning. In a gaze‐contingent eye‐tracking paradigm, infants in one condition were given the opportunity to structure their own information seeking to actively create word learning opportunities for themselves, while infants in two other conditions engaged in learning novel words passively. Infants’ learning of word‐object associations was compared across active and passive learning paradigms. The results indicate no advantage of active information selection on retention of novel words above and beyond passive learning, with infants across all conditions retaining novel words above chance. This study provides a crucial insight advancing our understanding of early word learning, and of the mechanisms and benefits of active, curiosity‐based learning in infants.

Background: Data-driven medical health information processing has become a new development trend in obstetrics. Electronic medical records (EMRs) are the basis of evidence-based medicine and an important information source for intelligent diagnosis. To obtain diagnostic results, doctors combine clinical experience and medical knowledge in their diagnosis process. External medical knowledge provides strong support for diagnosis. Therefore, it is worth studying how to make full use of EMRs and medical knowledge in intelligent diagnosis. Objective: This study aims to improve the performance of intelligent diagnosis in EMRs by combining medical knowledge. Methods: As an EMR usually contains multiple types of diagnostic results, the intelligent diagnosis can be treated as a multilabel classification task. We propose a novel neural network knowledge-aware hierarchical diagnosis model (KHDM) in which Chinese obstetric EMRs and external medical knowledge can be synchronously and effectively used for intelligent diagnostics. In KHDM, EMRs and external knowledge documents are integrated by the attention mechanism contained in the hierarchical deep learning framework. In this way, we enrich the language model with curated knowledge documents, combining the advantages of both to make a knowledge-aware diagnosis. Results: We evaluate our model on a real-world Chinese obstetric EMR dataset and showed that KHDM achieves an accuracy of 0.8929, which exceeds that of the most advanced classification benchmark methods. We also verified the model’s interpretability advantage. Conclusions: In this paper, an improved model combining medical knowledge and an attention mechanism is proposed, based on the problem of diversity of diagnostic results in Chinese EMRs. KHDM can effectively integrate domain knowledge to greatly improve the accuracy of diagnosis.

Purpose: The purpose of this study was to improve pre-service speech-language pathologists (SLPs) behavior management knowledge and self-efficacy through adaptive intervention options. Method: Using a sequential multiple-assignment randomized trial, we aimed to identify the best pathways to knowledge that considers an individual's response to instruction. We initially randomly assigned participants to either read a practitioner article or complete an online video module on two evidence-based behavior support practices.  Results: Through a series of re-randomizations and intervention components, results suggested that overall knowledge improved across participants regardless of intervention sequence. We intended to explore moderators of intervention efficacy (content engagement, self-efficacy) and assess social validity; however, our final sample was too small for a meaningful analysis.  Conclusion: Implementation of the SMART design was a challenge to full participation. We couch the discussion of our results in the context of the design, implementation, and areas of learning and promise, and directions for future research.

Pooling resources toward a shared goal is central to human cooperation, yet contributions often decline over time as free-riders (and the anticipation thereof) destabilize the interaction. Prior research highlights that incentives, norms, and preferences as stabilize cooperation, but has largely overlooked the role of when we decide—particularly in relation to one another. We propose that relational timing functions as a cue that shapes expectations of cooperation and as a signal of cooperative intent. We employed a repeated four-player public goods game (30 rounds), manipulating whether participants receive (a) timing feedback and (b) contribution feedback (2 x 2 between subjects design). We hypothesize that timing feedback increases cooperation. Competing process hypotheses predict that stable temporal dynamics reinforce cooperation most when contribution feedback is present (reinforcement hypothesis) or, alternatively, when it is absent (signaling hypothesis). Exploratory analyses examine how cooperation unfolds across rounds and whether temporal stability predicts sustained cooperation.

The UPPS-P Impulsive Behavior Scale is a well-established psychometric instrument for assessing impulsivity, a key multidimensional psychological construct encompassing distinct facets that are differentially associated with numerous psychopathological and neuropathological symptoms across various disorders. To facilitate its integration in clinical and research settings, Billieux et al. (2012) developed and evaluated the psychometric properties of a 20-item short version of the UPPS-P Impulsive Behavior Scale (UPPS-P-20), reducing assessment time to approximately one-third of that of the original version of the psychometric instrument. Despite its widespread popularity, legitimate concerns were raised about the content validity of this short version of the UPPS-P Impulsive Behavior Scale. Indeed, the inevitable loss of construct-level content coverage in short-form development, although often unaddressed by researchers, warrants in-depth examination. Therefore, the present registered report aimed to develop and evaluate the psychometric properties of a revised short version of the UPPS-P Impulsive Behavior Scale through an expert-driven and data-driven methodological approach to short-form development emphasizing item-level and construct-level content validity. Taken together, the present registered report provides professionals in clinical and research settings (1) a revised short English-language psychometric instrument for assessing impulsivity – i.e., the revised 20-item short version of the UPPS-P Impulsive Behavior Scale (UPPS-P-20-R) – that presents strong psychometric properties, notably addressing the legitimate concerns critically highlighted about the content validity of the UPPS-P-20, and (2) a data-driven methodological approach to construct-level content validity in short-form development – i.e., the R package shortr – that can be adopted to develop short versions of any psychometric instrument.

Response training, such as with the Go/NoGo task, reduces the value of trained items by requiring participants to repeatedly inhibit their responses to appetitive cues that typically elicit approach tendencies. This devaluation is thought to reflect a reduction in motivational conflict between cue-driven approach and task demand for response withholding. In this registered report, we examined whether individual differences in Pavlovian learning style, measured via a sign-tracking bias during a separate Pavlovian conditioning task, are associated with the topography of event-related potentials recorded during a food-related Go/NoGo task. We also assessed whether this bias correlates with participants’ reaction times and commission errors during the task.We found a covariance between sign-tracking bias and pre-training topographic electrophysiological responses during the P3 ERP component, but no association with training-induced plastic modification. Additionally, we found positive evidence for an absence of relationship between sign-tracking bias and behavioral responses at pre-training (r = 0.0, BF01 > 3), and weak evidence for its absence post-training (r = 0.1, BF01 < 3). These findings indicate that sign tracking bias modulates the activity of a specific brain network involved in inhibition of responses to appetitive cue. However, the absence of modulation induced by training suggests that food Go/NoGo training operates through pathways independent of the sign-tracking bias.

Dementia-causing diseases, including Alzheimer's disease (AD), are one of the greatest health concerns facing the aging world population. A key feature of AD is excessive accumulation of amyloid-beta, leading to synapse and cell loss in brain structures, such as the hippocampus. This neurodegeneration is preceded by impaired neuron function, notably reduced synaptic inhibition. Metabotropic GABAB receptors (GABABRs) may be modulated by amyloid precursor protein (APP) and are reported to be progressively lost from neuronal membranes of hippocampal pyramidal neurons. However, it remains unknown whether functional GABABR-mediated signaling changes over aging and whether or not pharmacological intervention can prevent receptor loss. In this study, we combine electrophysiological and biochemical analysis of hippocampal neurons in the Amyloid Precursor Protein/Presenilin-1 (APP/PS1) mouse model of AD from acute brain slices and organotypic slice cultures prepared from male and female mice to determine if functional GABABRs are lost and the effect of pharmacological modulation. Overall, we found that GABABR expression decreased with age, independent of genotype, with no evidence for postsynaptic GABABR loss in CA1 pyramidal cells at any age. We did observe a genotype-dependent reorganization of postsynaptic GABABR-mediated IPSCs, which was independent of age. Presynaptic GABABR-mediated inhibition was impaired in APP/PS1 mice, also independent of age. We observed that chronic GABABR modulation differentially regulated function but was independent of genotype. Overall, our data show that functional GABABR signaling is altered in APP/PS1 mice, independent of age, increasing our understanding of amyloidopathy-induced dysfunction.

A recommendation of: Peter Szecsi, Miklos Bognar, Barnabas Szaszi Do Scarcity-Related Cues Affect the Sustained Attentional Performance of the Poor and the Rich Differently? https://osf.io/preprints/psyarxiv/nk4d9_v3?view_only=

Background: eHealth interventions are widely used in clinical trials and increasingly in care settings as well; however, their efficacy in real-world contexts remains unknown. ReMindCare is a smartphone app that has been systematically implemented in a first episode of psychosis program (FEPP) for patients with early psychosis since 2018. Objective: The objective of this study was to assess the efficacy of ReMindCare after 19 months of use in the clinic and varying use by individual patients. Methods: The integration of the ReMindCare app into the FEPP started in October 2018. Patients with early psychosis self-selected to the app (ReMindCare group) or treatment as usual (TAU group). The outcome variables considered were adherence to the intervention and number of relapses, hospital admissions, and visits to urgent care units. Data from 90 patients with early psychosis were analyzed: 59 in the ReMindCare group and 31 in the TAU group. The mean age of the sample was 32.8 (SD 9.4) years, 73% (66/90) were males, 91% (83/90) were White, and 81% (74/90) were single. Results: Significant differences between the ReMindCare and TAU groups were found in the number of relapses, hospitalizations, and visits to urgent care units, with each showing benefits for the app. Only 20% (12/59) of patients from the ReMindCare group had a relapse, while 58% (18/31) of the TAU patients had one or more relapses (χ2=13.7, P=.001). Moreover, ReMindCare patients had fewer visits to urgent care units (χ2=7.4, P=.006) and fewer hospitalizations than TAU patients (χ2=4.6, P=.03). The mean of days using the app was 352.2 (SD 191.2; min/max: 18-594), and the mean of engagement was 84.5 (SD 16.04). Conclusions: To our knowledge, this is the first eHealth intervention that has preliminarily proven its benefits in the real-world treatment of patients with early psychosis.

Background: Mobile health (mHealth) apps provide innovative solutions for improving treatment adherence, facilitating lifestyle modifications, and optimizing blood pressure control in patients with hypertension. Despite their potential benefits, the adoption and recommendation of mHealth apps by physicians in Germany remain limited. This reluctance may be due to a lack of understanding of the factors influencing physicians’ willingness to incorporate these digital tools into routine clinical practice. Understanding these factors is crucial for fostering greater integration of mHealth apps in hypertension care. Objective: The aim of this study was to explore the relationship between physicians’ information needs and acceptance factors, and how these elements can support the effective integration of mHealth apps into daily medical routines. Methods: We conducted a qualitative study involving 24 semistructured telephone interviews with physicians, including 14 cardiologists and 10 general practitioners, who are involved in the treatment of hypertensive patients. Participants were selected through purposive sampling to ensure a diverse range of perspectives. Thematic analysis was conducted using MAXQDA software (Verbi GmbH) to identify key themes and subthemes related to the acceptance and use of mHealth apps. Results: The analysis revealed significant variability in physicians’ information needs regarding mHealth apps, particularly concerning their functionalities, clinical benefits, and potential impact on patient outcomes. These informational gaps play a critical role in determining whether physicians are willing to recommend mHealth apps to their patients. Key determinants influencing acceptance were identified, including the availability of robust knowledge about the apps, high-quality and reliable data, generational shifts within the medical profession, solid evidence supporting the effectiveness of the mHealth apps, and clearly defined areas of application and responsibilities within the physician-patient relationship. The study found that acceptance of mHealth apps could be significantly increased through targeted educational initiatives, enhanced data quality, and better integration of these tools into existing clinical workflows. Furthermore, younger physicians, more familiar with digital technologies, demonstrated greater openness to using mHealth apps, suggesting that generational changes may drive future increases in adoption. Conclusions: The successful integration of mHealth apps into hypertension management requires a multifaceted approach that addresses both the informational and practical concerns of physicians. By disseminating comprehensive knowledge about the variety, functionality, and proven efficacy of hypertension-related mHealth apps, health care providers can be better equipped to use these tools effectively. This approach necessitates the implementation of various knowledge transfer strategies, such as targeted training programs, peer learning opportunities, and active engagement with digital health technologies. As physicians become more informed and confident in the use of mHealth apps, their acceptance and recommendation of these tools are likely to increase, leading to more widespread adoption. Overcoming current barriers related to information deficits and data quality is essential for ensuring that mHealth apps are optimally used in routine hypertension care, ultimately improving patient outcomes and enhancing the overall quality of care. Trial Registration: German Clinical Trials Register DRKS00029761; https://drks.de/search/de/trial/DRKS00029761

Musicians are often regarded as a positive example of brain plasticity and associated cognitive benefits. This emerges when experienced musicians (e.g., musicians with more than 10 years of music training and practice) are compared with nonmusicians. A frequently observed behavioral finding is a short-term memory advantage of the former over the latter. Although available meta-analysis reported that the effect size of this advantage is medium (Hedges’s g = 0.5), no literature study was adequately powered to estimate reliably an effect of such size. This multilab study has been ideated, realized, and conducted in lab by several groups that have been working on this topic. Our ultimate goal was to provide a community-driven shared and reliable estimate of the musicians’ short-term memory advantage (if any) and set a method and a standard for future studies in neuroscience and psychology comparing musicians and nonmusicians. Thirty-three research units recruited a total of 600 experienced musicians and 600 nonmusicians, a number that is sufficiently large to estimate a small effect size (Hedges’s g = 0.3) with a high statistical power (i.e., 95%). Subsequently, we measured the difference in short-term memory for musical, verbal, and visuospatial stimuli. We also looked at cognitive, personality, and socioeconomic factors that might mediate the difference. Musicians had better short-term memory than nonmusicians for musical, verbal, and visuospatial stimuli with an effect size of, respectively, Hedges’s gs = 1.08 (95% confidence interval [CI] = [0.94, 1.22]; large), 0.16 (95% CI = [0.02 0.30]; very small), and 0.28 (95% CI = [0.15, 0.41]; small). This work sets the basis for sound research practices in studies comparing musicians and nonmusicians and contributes to the ongoing debate on the possible cognitive benefits of musical training.

In 2015, the city of São Paulo, Brazil, began providing free public transportation to all secondary education students enrolled in public schools, benefiting nearly 1.5 million teenagers since its implementation. This study aims to evaluate the impacts of this policy, examining both short-term outcomes, such as secondary education enrollment, completion, proficiency, and concurrent participation in the formal labor market, as well as medium-term outcomes, including higher education enrollment, formal labor market participation, and wages after completing school. The analysis leverages a rich longitudinal dataset that tracks all Brazilian students through basic and higher education, as well as their participation in the formal labor market, from 2007 to 2023. To identify the policy’s impacts, we will implement a difference-in-differences strategy, comparing changes in outcomes for students in São Paulo after the policy’s adoption with changes observed for students in other Brazilian cities attending schools with similar pre-treatment characteristics. Additionally, we will examine heterogeneity in policy effects within São Paulo by comparing changes in outcomes between neighborhoods with higher and lower levels of public transportation accessibility. A preliminary analysis, based on this empirical strategy and using publicly available school-level data, estimated reductions in dropout rates of up to 3.4% in the first year of secondary education following the policy’s implementation. The individual-level analysis proposed in this registered report has already been approved and will be conducted in the Brazilian Ministry of Education’s Protected Data Room between August and September 2025.

Self-management in chronic kidney disease (CKD) can slow disease progression; however, there are few tools available to support patients with early CKD. My Kidneys My Health is a patient-focused electronic health (eHealth) self-management tool developed by patients and caregivers. This study will investigate the implementation of My Kidneys My Health across primary care and general nephrology clinics. The study aims to: (1) identify and address barriers and facilitators that may impact implementation and sustainability of the website into routine clinical care; (2) evaluate implementation quality to inform spread and scale-up. We will conduct a multi-stage approach using qualitative methods, guided by the Quality Implementation Framework and using a qualitative content analysis approach. First, we will identify perceived barriers and facilitators to implementation and considerations for sustainability through interviews with clinicians, based on the Readiness Thinking Tool and the Long Term Success Tool. Analysis will be guided by the Consolidated Framework for Implementation Research and the Theoretical Domains Framework. Appropriate implementation strategies will be identified using the Expert Recommendations for Implementing Change compilation, and implementation plans will be developed based on Proctor’s recommendations and the Action, Actor, Context, Target, Time framework. Finally, we will explore implementation quality guided by the RE-AIM framework. There is limited literature describing systematic approaches to implementing and sustaining patient-focused self-management tools into clinical care, in addition to employing tailored implementation strategies to promote adoption and sustainability. We aim to generate insights on how My Kidneys My Health can be integrated into clinical care and how to sustain use of patient-centric eHealth tools in clinical settings on a larger scale.

Objectives Loneliness is a public health issue impacting the health and well-being of older adults. This protocol focuses on understanding the psychological experiences of loneliness in later life to inform technology development as part of the ‘Design for health ageing: a smart system to detect loneliness in older people’ (DELONELINESS) study. Methods and analysis Data will be collected from semi-structured interviews with up to 60 people over the age of 65 on their experiences of loneliness and preferences for sensor-based technologies. The interviews will be audio-recorded, transcribed and analysed using a thematic codebook approach on NVivo software. Ethics and dissemination This study has received ethical approval by Research Ethics Committee’s at King’s College London (reference number: LRS/DP-21/22-33376) and the University of Sussex (reference number: ER/JH878/1). All participants will be required to provide informed consent. Results will be used to inform technology development within the DELONELINESS study and will be disseminated in peer-reviewed publications and conferences.

Numerous studies show that prosocial behavior leads to positive emotional outcomes for the actor, yet does it matter, who the beneficiary is? The present paper explores differential effects of helping acts towards close versus distant recipients on subjective well-being and the role that basic psychological needs play in this relationship. Two studies using event-recall (N = 127) and interventional (N = 305) designs in Russian samples were conducted to test our hypotheses. Study 1 showed that performing acts of kindness towards family and friends (compared to a control condition) led to higher satisfaction of the needs for relatedness and morality, while helping strangers increased only the latter. Study 2 failed to unconditionally replicate the prosocial-happiness link; however, when the need for competence was controlled for, helping both types of recipients was shown to provide higher event-level well-being outcomes. The positive effect of prosocial acts toward strong ties was mediated by relatedness and morality satisfaction, while when the recipient was a stranger, the effect was accounted for by fulfilling the needs for morality and autonomy. No significant event-level well-being differences were detected between those helping close versus distant others and no differences in positive affect, negative affect or life satisfaction emerged between the three conditions. The paper provides support for the importance of the self-perceived impact for the success of kindness interventions. We conclude with a discussion of implications for kindness interventions towards different recipients.

This Registered Report examines urban-rural tensions in Sweden – a historically egalitarian, multi-party welfare state with strong geographical equalization schemes, making it a least-likely case for place-based resentment theories. Using an online survey experiment (n = 2,051), we measured resentment through perceptions of in-group and out-group, and by experimentally varying whether political statements came from rural or urban politicians. Rural respondents showed stronger in-group identification, greater place-based resentment, and more negative stereotypes of their out-group than urban respondents. However, we find no evidence of place-based bias – that is, that rural respondents are less receptive to urban politicians’ statements, or vice versa. These findings reveal clear urban-rural tensions in a context often considered unlikely for such divides, underscoring the role of regional identities in political discourse and policy in multi-party welfare states beyond Anglo-Saxon settings, while indicating that these tensions do not translate into systematic bias in evaluating political statements.

Psychological measures frequently show trait-like properties, and the ontological status of stable psychological traits has been discussed for decades. We argue that these properties can emerge from causal dynamics of time-varying processes, which are omitted from the analysis model, potentially leading to the estimation of traits that are, at least in part, illusory. Theories positing the importance of a large set of dynamic psychological causes across development are consistent with the existence of illusory traits. We show via simulation that even a linear system with many processes can generate a covariance matrix with trait-like properties. We then attempt to examine how illusory traits affect our conclusions drawn from a common statistical model, which assumes stable traits to analyze longitudinal panel data—a random-intercept cross-lagged panel model (RI-CLPM). We find that the RI-CLPM sometimes falsely detects the existence of traits in the presence of omitted processes, even when the data-generating model does not include any traits. However, in this scenario, the RI-CLPM estimates less causally biased autoregressive and cross-lagged effects than an analysis model, which does not assume traits (i.e., the cross-lagged panel model). The results indicate that the detection of trait variance should not be inferred as strong evidence for the existence of time-invariant trait causes. On the other hand, even when traits are illusory, statistical models assuming stable traits may sometimes be useful for causal inference. (PsycInfo Database Record (c) 2026 APA, all rights reserved)

Objective: We replicated research by ten Brinke and Porter (2012), who reported that a combination of four behavioral cues (word count, tentative words, upper face surprise, lower face happiness) could accurately discriminate deceptive murderers from genuinely distressed individuals, pleading for the return of a missing relative. Hypotheses: We hypothesized that each of the four behavioral cues identified in the original study would be similarly related (i.e., size, direction, significance) to veracity in a novel set of pleaders. With these cues as predictors, we also hypothesized that logistic regression models—separately testing the original and replication samples—would produce similar accuracy rates exceeding chance in discriminating genuine from deceptive pleaders. Method: We gathered a new sample of public appeals, including 82 genuine and 14 deceptive pleaders. After establishing ground truth, we transcribed video-recorded pleas and coded them for the presence of upper face surprise and lower face happiness. We used Linguistic Inquiry and Word Count to determine word count and the proportion of tentative words in each appeal. Results: We found support for several hypotheses. Tentative words were used significantly more by deceptive (vs. genuine) pleaders in both the original and replication samples. Deceptive pleaders used significantly fewer words in both samples, although this relationship was significant only in the original sample. Liars in both samples smiled more than truth-tellers, although this relationship was statistically significant only in the replication sample. However, predictive accuracy was poor and did not differ from chance in the replication sample. Conclusions: Findings do not provide a tidy picture of the reliability of behavioral cues to deception. Although some behavioral cues did replicate across samples, others did not. More research will be necessary to understand the factors that produce variable findings across samples, despite using the same methods of investigation. (PsycInfo Database Record (c) 2025 APA, all rights reserved)

When, during language processing, a reader or listener is confronted with a structurally deviant phrase, this typically elicits a late positive ERP deflection (P600). The P600 is often understood as a correlate of structural analysis. This assumption has informed a number of neurocognitive models of language. However, the P600 strongly resembles the P3, likely a more general electrophysiological correlate of reorientation behaviour supported by noradrenergic input to the ventral attention network/VAN. Some researchers have proposed that the P600 is an instance of the P3, not a distinct component reflecting the analysis of structured inputs. Here, we tested the P600-as-P3 hypothesis by estimating the alignment of the P600 elicited in a visual sentence processing task to simultaneously collected behavioural measures. A similar analysis was undertaken for a P3 elicited in a separate non-linguistic (face detection) task. Since the P3 is usually aligned to reaction time/RT, the same should hold for the P600; a failure to find RT alignment of the P600 would pose a problem for the P600-as-P3 hypothesis. In contrast, RT alignment of the P600 would associate it with the well-established VAN/Locus Coeruleus – Noradrenaline – Network subserving cortical reorientation. We failed to falsify the hypothesis of RT alignment. Secondary measures, while less unambiguous, were more in agreement with the P600-as-P3 hypothesis. We interpret our results as corroborating the hypothesis that the P600 is a P3, in that it shows that the P600 is RT-aligned. This perspective is unpredicted by an account of the P600 as indexing high-level processing.

When interacting with objects, we have to represent their location relative to our bodies. To facilitate bodily reactions, location may be encoded in the brain not just with respect to the retina (retinotopic reference frame), but also in relation to the head, trunk or arm (collectively spatiotopic reference frames). While spatiotopic reference frames for location encoding can be found in brain areas for action planning, such as parietal areas, there is debate about the existence of spatiotopic reference frames in higher-level occipitotemporal visual areas. In an extensive multi-voxel pattern analysis (MVPA) fMRI study using faces, headless bodies and scenes stimuli, Golomb and Kanwisher (2012) did not find evidence for spatiotopic reference frames in shape-selective occipitotemporal cortex. This finding is important for theories of how stimulus location is encoded in the brain. It is possible, however, that their failure to find spatiotopic reference frames is related to their stimuli: we typically do not manipulate faces, headless bodies or scenes. It is plausible that we only represent body-centred location when viewing objects that are typically manipulated. Here, we tested for object location encoding in shape-selective occipitotemporal cortex using manipulable object stimuli (balls and cups) in a MVPA fMRI study. We employed Bayesian analyses to determine sample size and evaluate the sensitivity of our data to test the hypothesis that location can be encoded in a spatiotopic reference frame in shape-selective occipitotemporal cortex over the null hypothesis of no spatiotopic location encoding. We found strong evidence for retinotopic location encoding consistent with previous findings that retinotopic reference frames are common neural representations of object location. In contrast, when testing for spatiotopic encoding, we found evidence that object location information for small manipulable objects is not decodable in relation to the body in shape-selective occipitotemporal cortex. Post-hoc exploratory analyses suggested that spatiotopic aspects might modulate retinotopic location encoding. Overall, our findings provide evidence that there is no spatiotopic encoding that is independent of retinotopic location in shape-selective occipitotemporal cortex.

Mu suppression has been proposed as a signature of the activity of the human mirror neuron system (MNS). However the mu frequency band (8–13 Hz) overlaps with the alpha frequency band, which is sensitive to attentional fluctuation, and thus mu suppression could potentially be confounded by changes in attentional engagement. The specific baseline against which mu suppression is assessed may be crucial, yet there is little consistency in how this is defined. We examined mu suppression in 61 typical adults, the largest mu suppression study so far conducted. We compared different methods of baselining, and examined activity at central and occipital electrodes, to both biological (hands) and non-biological (kaleidoscope) moving stimuli, to investigate the involvement of attention and alpha activity in mu suppression. We also examined changes in beta power, another candidate index of MNS engagement. We observed strong mu suppression restricted to central electrodes when participants performed hand movements, demonstrating that mu is indeed responsive to the activity of the motor cortex. However, when we looked for a similar signature of mu suppression to passively observed stimuli, the baselining method proved to be crucial. Selective suppression for biological versus non-biological stimuli was seen at central electrodes only when we used a within-trial baseline based on a static stimulus: this method greatly reduced trial-by-trial variation in the suppression measure compared with baselines based on blank trials presented in separate blocks. Even in this optimal condition, 16–21% of participants showed no mu suppression. Changes in beta power also did not match our predicted pattern for MNS engagement, and did not seem to offer a better measure than mu. Our conclusions are in contrast to those of a recent meta-analysis, which concluded that mu suppression is a valid means to examine mirror neuron activity. We argue that mu suppression can be used to index the human MNS, but the effect is weak and unreliable and easily confounded with alpha suppression.

Universities and higher education institutions form an integral part of the national infrastructure and prestige. As academic research benefits increasingly from international exchange and cooperation, many universities have increased investment in improving and enabling their global connectivity. Yet, the relationship of university performance and its global physical connectedness has not been explored in detail. We conduct, to our knowledge, the first large-scale data-driven analysis into whether there is a correlation between university relative ranking performance and its global connectivity via the air transport network. The results show that local access to global hubs (as measured by air transport network betweenness) strongly and positively correlates with the ranking growth (statistical significance in different models ranges between 5% and 1% level). We also found that the local airport’s aggregate flight paths (degree) and capacity (weighted degree) has no effect on university ranking, further showing that global connectivity distance is more important than the capacity of flight connections. We also examined the effect of local city economic development as a confounding variable and no effect was observed suggesting that access to global transportation hubs outweighs economic performance as a determinant of university ranking. The impact of this research is that we have determined the importance of the centrality of global connectivity and, hence, established initial evidence for further exploring potential connections between university ranking and regional investment policies on improving global connectivity.

In the field of evaluative conditioning (EC), two opposing theories—propositional single-process theory versus dual-process theory—are currently being discussed in the literature. The present set of experiments test a crucial prediction to adjudicate between these two theories: Dual-process theory postulates that evaluative conditioning can occur without awareness of the contingency between conditioned stimulus (CS) and unconditioned stimulus (US); in contrast, single-process propositional theory postulates that EC requires CS-US contingency awareness. In a set of three studies, we experimentally manipulate contingency awareness by presenting the CSs very briefly, thereby rendering it unlikely to be processed consciously. We address potential issues with previous studies on EC with subliminal or near-threshold CSs that limited their interpretation. Across two experiments, we consistently found an EC effect for CSs presented for 1000 ms and consistently failed to find an EC effect for briefly presented CSs. In a third pre-registered experiment, we again found evidence for an EC effect with CSs presented for 1000 ms, and we found some indication for an EC effect for CSs presented for 20 ms.

The vestibular system has widespread connections in the central nervous system. Several activation loci following vestibular stimulations have been notably reported in deep, limbic areas that are otherwise difficult to reach and modulate in healthy subjects. Following preliminary evidence, suggesting that such stimulations might affect mood and affective processing, we wondered whether the vestibular system is also involved in motivation. Evolutionary accounts suggest that visuo-vestibular mismatches might have a role in preventing the search for and exploitation of goods that previously resulted in aversive reactions, as they would be a fine warning signal which follows the contact with or ingestion of noxious neurotoxins. The first question was thus whether vestibular stimulation alters sensitivity to reward. Secondly, we sought to assess whether attention is allocated in space differently when cued by highly motivational stimuli, and if this interplay is further modulated by the vestibular system. In order to evaluate both motivational and attentional assets, we administered a Posner-like cueing task to 30 healthy subjects concurrently receiving sham or galvanic vestibular stimulation (GVS; Left-Anodal and Right-Anodal configurations). The participants had to discriminate targets appearing in either exogenously cued or uncued locations (50% validity); cues predicted the amount of points (0, 2, or 10) and thus money that they could earn for a correct response. The results highlight a robust inhibition of return (IOR) (faster responses for invalidly-cued targets) which was not modulated by different levels of reward or GVS. Across all stimulation sessions, rewards exerted a powerful beneficial effect over performance: reaction times were faster when rewards were at stake. However, this effect was largest in sham, but greatly reduced in GVS conditions, most notably with the Right-Anodal configuration. This is the first evidence for a decreased sensitivity to rewards causally induced by a perturbation of the vestibular system. While future studies will shed light on its neural underpinnings and clinical implications, here we argue that GVS could be a safe and promising way to enrich our understanding of reward processes and eventually tackle the management of patients with aberrant sensitivity to rewards.

Past research on action observation and imitation suggests that observing a movement activates a corresponding motor representation in the observer. However, recent research suggests that individuals may not only reflexively simulate the observed behavior but also simulate and engage in anticipated action without another person actually engaging in it. For example, it has been demonstrated that observing a triggering event (i.e., nose wrinkling) that potentially leads to the anticipation of an action (i.e., nose scratching) increases the likelihood that the observer will perform that action. In the present research, we applied motor Transcranial Magnetic Stimulation (TMS) to investigate such anticipated social action effects at the neurophysiological level within a trial-by-trial measure. While a pilot study suggests that observing nose wrinkling elicits stronger motor evoked potentials (MEPs) in participants' biceps muscles than observing control events, this effect could not be fully replicated in a preregistered study. Although a post hoc meta-analysis across both studies supports the general hypothesis, these results need to be taken cautiously. Implications of the results reported in the manuscript are discussed.

Previous findings indicate that facilitation of primary motor cortex (PMC) activity using trans-cranial direct current stimulation (tDCS) could improve resistance to physical fatigue. However, studies have failed to consistently replicate these results. Using non-focal-tDCS during a fatiguing task, recent work showed no enhancement of corticospinal excitability of the PMC despite a longer endurance time and suggested that contamination in other brain regions involved in motor command may have occurred. In accordance with recent evidence supporting the role of the prefrontal cortex (PFC) in exercise maintenance, this double-blind sham-controlled crossover study (N = 22) compared the effect of high definition (HD)-tDCS of the PMC or the PFC on endurance time of a sustained contraction task of the elbow flexor. Brain activity was monitored using near infrared spectroscopy (NIRS) to measure the neurovascular response elicited by HD-tDCS. Electromyography (EMG) and force obtained during maximal voluntary and evoked contractions were assessed before and after the contraction task to explore the effect of brain stimulation on peripheral and central fatigue. While the stimulation affected the brain response in the PFC during the contraction task, no effects of the stimulation were observed on endurance time or fatigue indices. These results are discussed in relation to the neurocognitive models of physical effort.

The role of the gut microbiota in carcinogenesis is increasingly being acknowledged. Recent studies in multiple breast cancer mouse models have found that antibiotics, by altering the gut microbiota, can accelerate tumour growth. In humans, a recent cohort study restricted to triple negative breast cancer showed that breast cancer patients using a greater number of antibiotics had markedly worse survival. These studies have raised concerns about repeated antibiotic use in breast cancer patients. In this Registered Report, we investigated whether breast cancer patients using oral antibiotics had increased breast cancer-specific mortality. In population-based cohorts (n = 44,452), we did not observe a statistically significant association between antibiotic prescriptions after diagnosis and breast cancer-specific mortality (adjusted HR = 1.07 95% CI 0.87, 1.33) apart from prescriptions of 12 or more antibiotics (adjusted HR = 1.62 95% CI 1.31, 2.01). This association was weaker after adjustment for infections (adjusted HR = 1.44 95% 1.14, 1.81), when restricted to antibiotics within five years (adjusted HR = 1.33 95% 0.95, 1.84), and was similar for deaths from other causes (adjusted HR = 1.69 95% 1.19, 2.41). Frequent antibiotic users had higher cancer-specific mortality but the attenuation of associations in sensitivity analyses, and similar findings for other causes of death, suggest this increase may reflect residual confounding. Protocol registration: The Stage 1 protocol for this Registered Report was accepted in principle on 7 November 2023. The protocol, as accepted by the journal, can be found at https://doi.org/10.6084/m9.figshare.24746721.v1.